RIL: Publications
Journal
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Research
Papers
78. Modo, M., Ghuman, H., Azar, R., Krafty, R., Badylak, S.F.,
Hitchens, T.K. Mapping the acute time course of immune cell infiltration into
an ECM hydrogel in a rat model of stroke using 19F MRI.
Biomaterials. 2022, 282: 121386. PMID: 35093825.
77. Ghuman, H., Perry, N., Grice, L., Gerwig, M., Moorhead, J., Nitzsche,
F., Poplawsky, A., Ambrosio, F., Modo, M. Physical
therapy exerts sub-additive and suppressive effects on intracerebral neural
stem cell implantation in a rat model of stroke. Journal of Cerebral Blood Flow
and Metabolism. 2021, 41(1): 1-18. PMID: 34826373. Cover Image.
76. Damian, C., Ghuman, H., Mauney, C., Azar, R., Reinartz,
J., Badylak, S.F., Modo, M.
Post-stroke timing of ECM hydrogel implantation affects biodegradation and
tissue restoration. International Journal for Molecular Sciences. 2021, 22(21):
11372. PMID: 34768800.
75. Ghuman, H., Matta, R., Tompkins, A., Nitzsche, F., Badylak, S.,
Gonzalez, A., Modo, M. ECM hydrogel improves the delivery and retention of stem
cell encapsulating PEG microspheres in a stroke cavity. Brain Research
Bulletin. 2021, 168-120-137. PMID: 33373665.
74. Ke, J., Foley, L., Hitchens, T.K.,
Richardson, M., Modo, M. Ex vivo mesoscopic diffusion MRI correlates with
seizure frequency in patients with uncontrolled temporal lobe epilepsy. Human
Brain Mapping 2020; 41: 4529-4548. PMID: 326221364. Cover Image.
73. Ly, M., Foley, L., Manivannan, A.,
Hitchens, T.K., Richardson, M., Modo, M. Mesoscale diffusion MR imaging of the ex vivo human hippocampus. Human Brain
Mapping. 2020; 41(15):4200-4218. PMID: 32621364. Cover Image.
72. Chou, C.H. & Modo, M. Characterization of gene expression
changes in human neural stem cells and endothelial cells modeling a
neurovascular environment. Brain Research Bulletin. 2020; 158: 9-19. PMID: 32092433.
71. Ghuman, H., Hitchens, K., Modo, M. A
systematic optimization of 19F MR image acquisition to detect
macrophage invasion into an ECM hydrogel implanted in the stroke-damaged brain.
Neuroimage. 2019; 202. PMID: 31408717.
70. Ghuman, H., Mauney,
C., Donnelly, J., Massensini, A., Badylak,
S.F., Modo, M. Biodegradation of ECM hydrogel
promotes endogenous brain tissue restoration in a rat model of stroke. Acta Biomaterialia 2018; 80: 66-84. PMID: 30232030.
69. Wahlberg, B., Ghuman, H., Liu, J.R.,
Modo, M. Ex vivo biomechanical characterization of syringe-needle ejections for
intracerebral cell delivery. Scientific Reports. 2018; 8: 9194. PMID: 29907825.
68. Calvero, A., Cotel,
M.-C., Natesan, S., Modo, M., Vernon, A.C., Mondelli,
V. Effects of chronic antipsychotic treatment on expression of TSPO and
inflammatory markers in rat adipose tissue. Psychoneuroendocrinology.
2018; 95: 28-33. PMID: 29793094.
67. Liu, J, Modo, M. Quantification of the extracellular matrix
molecule thrombospondin 1 and its cellular association in the brain using a
semi-automated computerized approach. J Histochemistry & Cytochemistry.
2018; 66(9): 643-662. PMID: 29683384. Cover Image.
66. Jin, T., Iordanova,
B., Hitchens, T.K., Modo, M., Wang, P., Mehrens, H.,
Kim, S.G. Chemical exchange-sensitive spin-lock (CESL) MRI of glucose and
analogs in brain tumors. Magnetic Resonance in Medicine. 2018; 80(2):488-495. PMID: 29569739.
65. Ghuman, H. Gerwig,
M., Nicholls, F.J., Liu, J., Donnelly, J., Badylak,
S.F., Modo, M. Long-term retention of ECM hydrogel
after implantation into a sub-acute stroke cavity reduces lesion volume. Acta Biomaterialia. 2017; 50-63. PMID: 28917705.
64. Dalise, S., Cavalli, L., Ghuman, H., Wahlberg, B., Gerwig,
M., Chisari, C., Ambrosio, F., Modo, M. Biological effects
of dosing aerobic exercise and neuromuscular electrical stimulation in rats.
Scientific Reports. 2017; 7(1): 10830. PMID: 28883534.
63. Modo, M., Crum, W.R., Gerwig, M.,
Vernon, A.C., Patel, P., Jackson, M.J., Rose, S., Jenner, P., Iravani, M.M. Magnetic resonance imaging and tensor-based
morphometry in the MPTP non-human primate model of Parkinson’s disease. PLOS1.
2017; 12(7): e0180733. PMID: 28738061.
62. Nicholls, F.J., Liu, J.R., Modo, M. A comparison of exogenous
labels for the histological identification of transplanted neural stem cells.
Cell Transplantation. 2017; 26: 625-645. PMID: 27938486. Cover Image.
61. Rattray, I., Smith, E., Crum, W., Walker, T., Bates, G., Modo,
M. Correlations of behavioral deficits with brain pathology assessed through
longitudinal MRI and histopathology in the HdhQ150/Q150
mouse model of Huntington’s disease. PLOS1. 2017; 18(2): e0168556. PMID: 28088507.
60.
Jin, T., Nicholls, F.J., Ghuman, H., Badylak, S.F., Modo, M. Diamagnetic
chemical exchange saturation transfer (dia-CEST) affords magnetic resonance
imaging of extracellular matrix hydrogel implantation in a rat model of stroke.
Biomaterials. 2017; 113:176-190. PMID: 27816001.
59.
Crum, W.R., Danckaers, F., Huysmans, T., Natesan, S., Modo, M., Sijbers, J.,
Williams, S.C.R., Kapur, S., Vernon, A.C. Chronic treatment with haloperidol
and olanzapine leads to common and divergent shape changes in the rat
hippocampus in the absence of grey matter volume loss. Psychological Medicine.
2016; 46: 3081-3093. PMID: 27516217.
58.
Chou, C-H., Modo, M. Human neural stem cell-induced endothelial morphogenesis
requires paracrine and juxtacrine signaling. Scientific Reports. 2016; 6:
29029. PMID: 27374240.
57.
Ghuman, H., Massensini, A, Kim, T., Badylak, S.F., Modo, M. ECM hydrogel
injection for the treatment of stroke: Characterization of the acute host cell
invasion. Biomaterials. 2016; 91: 166-181. PMID: 27031811.
56.
Modo, M., Hitchens, T.K., Liu, J., Richardson, R.M. Ex vivo mesoscale diffusion
MRI reveals an aberrant collateral mossy fiber connection between dentate gyrus
and the stratum moleculare layer in a patient with uncontrolled temporal lobe
epilepsy. Human Brain Mapping. 2016; 37(2):780-795. PMID: 26611565.
55.
Rossetti, T., Nicholls, F., Modo, M. Intracerebral cell transplantation:
Preparation and characterization of cell suspensions. Cell Transplantation.
2016; 25: 645-664. PMID: 26720923.
54.
Nicholls, F., Rotz, M.W., Ling, W., Ghuman, H., MacRenaris, K.W., Meade, T.J.,
Modo, M. DNA-Gadolinium-Gold nanoparticles for in vivo T1 MR imaging of
transplanted human neural stem cells. Biomaterials. 2016; 77: 291-306. PMID: 26615367.
53.
Nicholls, F., Ling, W., Ferrauto, G., Aime, S., Modo, M. Simultaneous MR
imaging for tissue engineering in a rat model of stroke. Scientific Reports.
2015; 5: 14597. PMID: 26419200.
52.
Massensini, A., Ghuman, H., Medberry, C.J., Ling, W., Nicholls, F.J., Badylak,
S.F., Modo, M. Concentration-dependent intracerebral delivery of ECM hydrogel
to a stroke cavity. Acta Biomaterialia. 2015; 27:116-130. PMID: 26318805.
51.
Cotel, M.-C., Lenartowicz, E.M., Natesan, S., Modo, M., Cooper, J.D., Williams,
S.C.R., Kapur, S., Vernon, A.C. Region-specific microglia activation in the rat
brain following chronic antipsychotic treatment at clinically relevant doses.
European Neuropsychopharmacology. 2015; 25(11):2098-2107. PMID: 26321204.
50.
Caron, I., Micotti, E., Merlino, G., Plebani, L., Gianluigi, F., Modo, M.,
Bendotti, C. Comparative magnetic resonance imaging and histopathology
correlates in two SOD1 transgenic mouse models of amyotrophic lateral sclerosis.
PLOS1. 2015;10(7):e0132159. PMID: 26132656.
49.
Chou, C-H., Sinden, J.D., Couraud, P-O., Modo, M. In vitro modelling of the
neurovascular environment by coculturing adult human brain endothelial cells
with human neural stem cells. PLOS One. 2014: 9(9): e106346. PMID: 25187991.
48.
Rattray, I., Smith, E., Crum, W., Walker, T., Gale, R., Bates, G., Modo, M.
Correlations of behavioral deficits with brain pathology assessed through
longitudinal MRI and histopathology in the R6/1 mouse model of HuntingtonÕs
disease. PLOS One. 2013: 8(12): e84726. PMID: 24367693.
47.
Chung, Y.-L., El Akabawy, G., So, P-W., Solanky, B., Leach, M.O., Modo, M.
Profiling metabolite change in the neuronal differentiation of human striatal
neural stem cells using 1H-magnetic resonance spectroscopy.
NeuroReport. 2013: 24(18);1035-1040. PMID: 24145773.
46.
Alfieri, A., Srivastava, S., Siow, R.C.M., Cash, D., Modo, M., Duchen, M.R.,
Fraser, P.A., Williams, S.C.R., Mann, G.E. Sulforaphane preconditioning of the
Nrf2/HO-1 defence pathway protects the cerebral vasculature against blood-brain
barrier disruption and neurological deficits in stroke. Free Radical Biology
and Medicine. 2013: 65C; 1012-1022. PMID: 24017972.
45.
Vernon, A.C., Crum, W.R., Lerch, J.P., Chege, W., Natesan, S., Modo, M.,
Cooper, J.D., Williams, S.C.R., Kapur, S. Reduced cortical volume and elevated
astrocyte density in rats chronically treated with antipsychotic drugs –
linking MRI findings to cellular pathology. Biological Psychiatry. 2014,
75(12):982-990. PMID: 24143881.
44.
Kazanis, I., Gorenkova, N., Zhao, J.-W., Franklin, RJM, Modo, M.,
ffrench-Constant, C. The late response of rat subependymal zone stem and
progenitor cells to stroke is restricted to directly affected areas of their
niche. Experimental Neurology. 2013: 248; 387-397. PMID: 23830949.
43.
Stille, M., Smith, E., Crum, W.R., Modo, M. 3D reconstruction of 2D
fluorescence histology images and registration with in vivo MR images:
Application in a rodent model of stroke. Journal of Neuroscience Methods. 2013:
219 (1); 27-40. PMID: 23816399.
42.
Crum, W.R., Giampietro, V.P., Smith, E.J., Gorenkova, N., Stroemer, R.P., Modo,
M. A comparison of automated anatomical-behavioural mapping methods in a rodent
model of stroke. Journal of Neuroscience Methods. 2013: 218 (2); 170-183. PMID: 23727124.
41.
Crum, W.R., Modo, M., Vernon, A.C., Barker, G.J., Williams, S.C.R. Registration
of challenging pre-clinical brain imaging. Journal of Neuroscience Methods,
2013: 216 (1); 62-77. PMID: 23558335.
40.
dellÕAcqua, F, Bodi, I., Slater, D., Catani, M., Modo, M. MR diffusion-based
histology and micro-tractography reveal mesoscale features of the human
cerebellum. Cerebellum, 2013:12(6); 923-931. PMID: 23907655.
39.
Rattray, I., Smith, E., Gale, R., Matsumoto, K., Bates, G.P., Modo, M.
Correlations of behavioral deficits with brain pathology assessed through
longitudinal MRI and histopathology in the R6/2 mouse model of HuntingtonÕs
disease. PLoS One 2013: 8(4); e60012. PMID: 23593159.
38.
Mondelli, V, Anacker, C., Vernon, A.C., Cattaneo, A., Natesan, S., Modo, M.,
Dazzan, P., Kapur, S., Pariente, C. Haloperidol and olanzapine mediate
metabolic abnormalities through different molecular pathways. Translational
Psychiatry 2013: 3; e208. PMID: 23321805.
37.
Medberry, C.J., Crapo, P.M., Siu, B.F., Carruthers, C.A., Wolf, M.T., Nagarkar,
S., Agrawl, V., Jones, K.E., Kelly, J., Johnson, S.A., Sachin, V., Watkins,
S.C., Modo, M., Badylak. S.F. Hydrogels derived from central nervous system
extracellular matrix. Biomaterials. 2013: 34(4):1033-1040. PMID: 23158935.
36.
Puppi, J., Modo, M., Dhawan, A., Mitry, R.R., Hughes, R. Tracking transplanted
hepatocytes in a rat model of acute liver failure – is there a role for
cellular MRI? Cell Transplantation. 2014; 23(3):329-343. PMID: 23394812.
35.
El-Akabawy, G, Rattray, I., Johansson, S.M., Gale, R., Bates, G., Modo, M.
Implantation of undifferentiated and pre-differentiated human neural stem cells
in the R6/2 transgenic mouse model of HuntingtonÕs disease. BMC Neuroscience
2012: 13(1); 97. PMID: 22876937.
34.
Bible, E., Qutachi, O., Chau, D.Y., Alexander, M.R., Shakesheff, K.M., Modo, M.
Neo-vascularization of the stroke cavity by implantation of human neural stem
cells on VEGF-releasing PLGA microparticles. Biomaterials 2012: 33; 7435-7446. PMID: 22818980.
33.
Vernon, A.C., Natesan, S., Crum, W.R., Cooper, J.D., Modo, M., Williams,
S.C.R., Kapur, S. Contrasting effects of haloperidol and lithium on brain
structure: An MRI study with post-mortem confirmation. Biological Psychiatry.
2012: 71(10); 855-863. PMID: 22244831.
32.
Bible, E., DellÕAcqua, F., Solanky, B., Bladucci, A., Crapo, P., Badylak, S.F.,
Ahrens, E.T., Modo, M. Non-invasive imaging of transplanted human neural stem
cells and ECM scaffold remodelling in the stroke-damaged rat brain by 19F-
and diffusion-MRI. Biomaterials. 2012; 33, 2858-2871. PMID: 22244696.
31.
Smith, E.J., Stroemer, R.P., Gorenkova, N., Nakajima, M., Crum, W.R., Tang, E.,
Stevanato, L., Sinden, J.D., Modo, M. Implantation site and lesion topology
determine efficacy of a human neural stem cell line in a rat model of stroke.
Stem Cells, 30(4), 785-796. PMID: 22213183.
30.
Patkar, S., Tate, R., Modo, M., Pelvin, R. & Carswell, H.V.O. Conditionally
immortalised neural stem cells promote functional recovery and brain plasticity
after transient focal cerebral ischaemia in mice. Stem Cell Research. 2012:
8(1); 14-25. PMID:22099017.
29.
Vernon, AC, Smith, E., Stevanato, L., Modo, M. Selective activation of
metabotropic glutamate receptor 7 reduces proliferation and promotes astrocyte
differentiation in human ventral mesencephalic neural stem cells.
Neurochemistry International. 2011, Sep;59(3)421-31. Epub 2011 May 23 PubMed PMID: 21624409.
28.
Vernon AC, Crum WR, Johansson SM, Modo M. Evolution of extra-nigral damage
predicts behavioural deficits in a rat proteasome inhibitor model of
Parkinson's disease. PLoS One. 2011 Feb 25;6(2):e17269. PubMed PMID: 21364887.
27.
El Akabawy G, Martinez-Medina L, Jeffries AR, Price J, Modo M. Purmorphamine
increases DARPP-32 differentiation in human striatal neural stem cells through
the hedgehog pathway. Stem Cells Dev. 2011 Feb 23. [Epub ahead of print] PubMed
PMID: 21345011.
26.
Vernon AC, Natesan S, Modo M, Kapur S. Effect of Chronic Antipsychotic
Treatment on Brain Structure: A Serial Magnetic Resonance Imaging Study with Ex
Vivo and Postmortem Confirmation. Biol Psychiatry. 2011 May 15;69(10):936-44.
[Epub 2010 Dec 31] PubMed PMID: 21195390.
25.
Puppi J, Mitry RR, Modo M, Dhawan A, Raja K, Hughes RD. Use of a
Clinically-Approved Iron Oxide MRI Contrast Agent to Label Human Hepatocytes.
Cell Transplant. 2010 Nov 19. [Epub ahead of print] PubMed PMID: 21092412.
24.
Vernon AC, Johansson SM, Modo MM. Non-invasive evaluation of nigrostriatal
neuropathology in a proteasome inhibitor rodent model of Parkinson's disease.
BMC Neurosci. 2010 Jan 5;11:1. PubMed PMID: 20051106; PubMed Central PMCID: PMC2824797.
23.
Bible E, Chau DY, Alexander MR, Price J, Shakesheff KM, Modo M. Attachment of
stem cells to scaffold particles for intra-cerebral transplantation. Nat
Protoc. 2009;4(10):1440-53. Epub
2009 Sep 17. PubMed PMID: 19798079.
22.
Ashioti M, Beech JS, Lowe AS, Bernanos M, McCreary A, Modo MM, Williams SC.
Neither in vivo MRI nor behavioural assessment indicate therapeutic efficacy
for a novel 5HT(1A) agonist in rat models of ischaemic stroke. BMC Neurosci.
2009 Jul 16;10:82. PubMed PMID: 19607699; PubMed Central PMCID: PMC2720976.
21.
Bible E, Chau DY, Alexander MR, Price J, Shakesheff KM, Modo M. The support of
neural stem cells transplanted into stroke-induced brain cavities by PLGA
particles. Biomaterials. 2009 Jun;30(16):2985-94. Epub 2009 Mar 10. PubMed PMID: 19278723.
20.
Badin RA, Modo M, Cheetham M, Thomas DL, Gadian DG, Latchman DS, Lythgoe MF.
Protective effect of post-ischaemic viral delivery of heat shock proteins in
vivo. J Cereb Blood Flow Metab. 2009 Feb;29(2):254-63. Epub 2008 Sep 10. PubMed
PMID: 18781161; PubMed Central PMCID: PMC2702130.
19.
Roberts TJ, Williams SC, Modo M. A pharmacological MRI assessment of
dizocilpine (MK-801) in the 3-nitroproprionic acid-lesioned rat. Neurosci Lett.
2008 Oct 17;444(1):42-7. Epub 2008 Aug 5. PubMed PMID: 18703114.
18.
Johansson S, Price J, Modo M. Effect of inflammatory cytokines on major
histocompatibility complex expression and differentiation of human neural
stem/progenitor cells. Stem Cells. 2008 Sep;26(9):2444-54. Epub 2008 Jul 17.
PubMed PMID: 18635871.
17.
Modo M, Beech JS, Meade TJ, Williams SC, Price J. A chronic 1 year assessment
of MRI contrast agent-labelled neural stem cell transplants in stroke.
Neuroimage. 2009 Aug;47 Suppl 2:T133-42. Epub 2008 Jun 25. PubMed PMID: 18634886.
16.
Brekke C, Williams SC, Price J, Thorsen F, Modo M. Cellular multiparametric MRI
of neural stem cell therapy in a rat glioma model. Neuroimage. 2007 Sep
1;37(3):769-82. Epub 2007 Jun 14. PubMed PMID: 17613248.
15.
Bae JS, Han HS, Youn DH, Carter JE, Modo M, Schuchman EH, Jin HK. Bone
marrow-derived mesenchymal stem cells promote neuronal networks with functional
synaptic transmission after transplantation into mice with neurodegeneration.
Stem Cells. 2007 May;25(5):1307-16. PubMed PMID: 17470534.
14.
Ashioti M, Beech JS, Lowe AS, Hesselink MB, Modo M, Williams SC. Multi-modal
characterisation of the neocortical clip model of focal cerebral ischaemia by MRI,
behaviour and immunohistochemistry. Brain Res. 2007 May 11;1145:177-89. Epub
2007 Feb 2. PubMed PMID: 17320839.
13.
Wheatcroft SB, Kearney MT, Shah AM, Ezzat VA, Miell JR, Modo M, Williams SC,
Cawthorn WP, Medina-Gomez G, Vidal-Puig A, Sethi JK, Crossey PA. IGF-binding
protein-2 protects against the development of obesity and insulin resistance.
Diabetes. 2007 Feb;56(2):285-94. PubMed PMID: 17259371.
12.
Roberts TJ, Price J, Williams SC, Modo M. Pharmacological MRI of stem cell
transplants in the 3-nitropropionic acid-damaged striatum. Neuroscience. 2007
Jan 5;144(1):100-9. Epub 2006 Oct 19. PubMed PMID: 17055178.
11.
Brekke C, Morgan SC, Lowe AS, Meade TJ, Price J, Williams SC, Modo M. The in
vitro effects of a bimodal contrast agent on cellular functions and
relaxometry. NMR Biomed. 2007 Apr;20(2):77-89. PubMed PMID: 16952123.
10.
Roberts TJ, Price J, Williams SC, Modo M. Preservation of striatal tissue and
behavioral function after neural stem cell transplantation in a rat model of
Huntington's disease. Neuroscience. 2006;139(4):1187-99. Epub 2006 Mar 6.
PubMed PMID: 16517087.
9.
Modo M, Mellodew K, Cash D, Fraser SE, Meade TJ, Price J, Williams SC. Mapping
transplanted stem cell migration after a stroke: a serial, in vivo magnetic
resonance imaging study. Neuroimage. 2004 Jan;21(1):311-7. PubMed PMID: 14741669.
8.
Modo M, Hopkins K, Virley D, Hodges H. Transplantation of neural stem cells
modulates apolipoprotein E expression in a rat model of stroke. Exp Neurol.
2003 Oct;183(2):320-9. PubMed PMID: 14552873.
7.
Modo M, Stroemer RP, Tang E, Patel S, Hodges H. Effects of implantation site of
dead stem cells in rats with stroke damage. Neuroreport. 2003 Jan
20;14(1):39-42. PubMed PMID: 12544827.
6.
Modo M, Mellodew K, Rezaie P. In vitro expression of major histocompatibility class
I and class II antigens by conditionally immortalized murine neural stem cells.
Neurosci Lett. 2003 Feb 6;337(2):85-8. PubMed PMID: 12527394.
5.
Modo M, Rezaie P, Heuschling P, Patel S, Male DK, Hodges H. Transplantation of
neural stem cells in a rat model of stroke: assessment of short-term graft
survival and acute host immunological response. Brain Res. 2002 Dec
20;958(1):70-82. PubMed PMID: 12468031.
4.
Modo M, Cash D, Mellodew K, Williams SC, Fraser SE, Meade TJ, Price J, Hodges
H. Tracking transplanted stem cell migration using bifunctional, contrast
agent-enhanced, magnetic resonance imaging. Neuroimage. 2002 Oct;17(2):803-11.
PubMed PMID: 12377155.
3.
Modo M, Stroemer RP, Tang E, Patel S, Hodges H. Effects of implantation site of
stem cell grafts on behavioral recovery from stroke damage. Stroke. 2002
Sep;33(9):2270-8. PubMed PMID: 12215598.
2.
Modo M, Stroemer RP, Tang E, Veizovic T, Sowinski P, Hodges H. Neurological
sequelae and long-term behavioural assessment of rats with transient middle
cerebral artery occlusion. J Neurosci Methods. 2000 Dec 15;104(1):99-109.
PubMed PMID: 11163416.
1. Modo
M, Sowinski P, Hodges H. Conditional discrimination learning in rats with
global ischaemic brain damage. Behav Brain Res. 2000 Jun 15;111(1-2):213-21.
PubMed PMID: 10840146.
Reviews
31. Hussein, H., Kokkinos, V., Sisterson, N.D., Modo, M., Richardson, R.M. Extrapial hippocampal resection in anterior temporal lobectomy: Technical description and clinical outcomes. Operative Neurosurgery. 2021. 21(5): 312-323.
PMID: 34333663.
30. Modo, M. 19 F magnetic resonance imaging in neuroscience. Neuroscience. 2021:474:37-50.
PMID: 33766776.
29. Modo, M. Bioscaffold-induced brain tissue restoration. Frontiers in Neuroscience. 2019; 13:1156.
PMID: 31787865.
28. Boltze, J., Modo, M., Mays, R.R., Taguchi, A., Zille, M., Jolkkonen, J., Savitz, S. Stem cells as an emerging paradigm in stroke (STEPS) 4: Advancing and accelerating preclinical research. Stroke. 2019; 50(11):3299-3306.
PMID: 31658004.
27. Modo, M. & Badylak, S.F. A roadmap for promoting endogenous in situ tissue restoration using inductive bioscaffolds after acute brain injury. Brain Research Bulletin. 2019; 150: 136-149.
PMID: 31128250.
26. Modo, M., Jolkkonen, Zille, M., Boltze, J. Future of animal modeling for poststroke tissue repair. Stroke. 2018; 49(5): 1099-1106. PMID: 29669872.
25. Amer, M.H., Rose, F.R.A., Shakesheff, K.M., Modo, M., White, L.J. Translational considerations for injectable cell-based therapeutics: Concepts, progress and challenges. Npj Regenerative Medicine. 2017; 2(1): 23.
PMID: 29302358.
24.
Ghuman, H., & Modo, M. Biomaterial applications in neural therapy and
repair. Chinese Neurosurgical Journal. 2016; 2: 34.
23.
Modo, M. Gaining mechanistic insights into cell therapy using magnetic
resonance imaging. Current Stem Cell Reports. 2016; 2(3); 221-227.
22.
Dalise, S., Ambrosio, F., Modo, M. Brain plasticity and recovery in preclinical
models of stroke. Archives Italiennes de Biologie. 2014; 152(4): 190-215. PMID: 25987181.
21. Naumova, A.V., Modo, M., Moore, A., Murry, C.E., Frank, J.A.
Clinical imaging in regenerative medicine. Nature Biotechnology. 2014; 32(8):
804-818. PMID: 25093889.
20. Meng, F.W., Modo, M., & Badylak, S.F. Biologic scaffold for
central nervous system repair. Regenerative Medicine. 2014; 9(3): 367-383. PMID: 24935046.
19. Savitz, S., Cramer, S., Wechsler, L., Aronowski, J., Boltze, J.,
Borlongan, C., Chase, T., Chopp, M., Carmichael, S.T., Fischkoff, S., Guzman,
R., Hess, D., Huang, D., Hinson, J., Mitsias, P., Modo, M., Muir, K.,
Steinberg, G., Wolf, S., Yankee, E. Stem cells as an emerging paradigm for
stroke (STEPS3): enhancing the development of clinical trials. Stroke. 2014:
45(2); 634-639. PMID: 24368562.
18. Modo, M., Ambrosio, F., Friedlander, R., Badylak, S.F., Wechsler, L.
Bioengineering solutions for neural repair and recovery in stroke. Current
Opinion in Neurology. 2013: 26(6); 626-631. PMID: 24136127.
17. Modo, M., Kolosnjaj, J., Nicholls, F., Ling, W., Wilhelm, C.,
Debarge, O., Gazeau, F., Clement, O. Considerations for the clinical use of MRI
contrast agents for cell tracking in regenerative medicine. Contrast Media and
Molecular Imaging. 2013: 8(6); 439-455. PMID: 24375900.
16. Sztriha, L., Modo, M., Gorman, R., Baker, G., Williams, S.C., Kalra,
L. Monitoring brain repair in stroke using advanced magnetic resonance imaging.
Stroke, 2012; 43(11):3124-3131. PMID:23010674..
15. Evans, M.C., Modo, M., Talbot, K., Sibson, N., Turner, M.R. Magnetic
resonance imaging of pathological processes in rodent models of amyotrophic
lateral sclerosis. Amyotrophic Lateral Sclerosis. 2012; 13(3); 288-301. PMID: 22117132.
14. Modo, M. & Kinchin, I.
(2011). A conceptual framework for interdisciplinary curriculum design: A case
study in neuroscience. Journal of Undergraduate Neuroscience Education, 10(1),
A71-A79. PMID: 23626496.
13. Alfieri A, Srivastava S, Siow R, Modo M, Fraser P, Mann GE.
Targeting the Nrf2-Keap1 antioxidant defence pathway for neurovascular
protection in stroke. J Physiol. 589: 4125-4136. PubMed PMID: 21656410.
12. Kateb B, Chiu K, Black KL, Yamamoto V, Khalsa B, Ljubimova JY, Ding
H, Patil R, Portilla-Arias JA, Modo M, Moore DF, Farahani K, Okun MS, Prakash
N, Neman J, Ahdoot D, Grundfest W, Nikzad S, Heiss JD. Nanoplatforms for
constructing new approaches to cancer treatment, imaging, and drug delivery:
what should be the policy? Neuroimage. 2011 Jan; 54 Suppl 1:S106-24. PubMed PMID: 20149882.
11. Turner, M., Modo, M. Recent advances in the MR imaging of
Amyotrophic Lateral Sclerosis. Expert Opinion on Medical Diagnostics. 2010
4(6), 483-496. PubMed PMID: 215116259.
10. Vernon AC, Ballard C, Modo M. Neuroimaging for Lewy body disease: is
the in vivo molecular imaging of a-synuclein neuropathology required and
feasible? Brain Res Rev. 2010 Oct 5;65(1):28-55. Epub 2010 Jun 2. Review.
PubMed PMID: 20685363.
9. Modo M. Long-term survival and serial assessment of stroke damage and
recovery – practical and methodological considerations. Journal of
Experimental Stroke and Translational Medicine. 2010 2, 52-68.
8. Puppi J, Modo M. Use of magnetic resonance imaging contrast agents to
detect transplanted liver cells. Top Magn Reson Imaging. 2009 Apr;20(2):113-20.
Review. PubMed PMID: 20010066.
7. Modo M. Noninvasive imaging of transplanted cells. Curr Opin Organ
Transplant. 2008 Dec;13(6):654-8. Review. PubMed PMID: 19060558.
6. Modo M. Brain repair how stem cells are changing neurology. Bull Soc
Sci Med Grand Duche Luxemb. 2008;(2):217-57. Review. PubMed PMID: 18561598.
5. Modo M. Understanding stem cell-mediated brain repair through
neuroimaging. Curr Stem Cell Res Ther. 2006 Jan;1(1):55-63. Review. PubMed PMID: 18220854.
4. Schaller BJ, Modo M, Buchfelder M. Molecular imaging of brain tumors:
a bridge between clinical and molecular medicine? Mol Imaging Biol. 2007
Mar-Apr;9(2):60-71. Review. PubMed PMID: 17203238.
3. Modo M, Hoehn M, Bulte JW. Cellular MR imaging. Mol Imaging. 2005
Jul-Sep;4(3):143-64. Review. PubMed PMID: 16194447.
2. Modo M, Roberts TJ, Sandhu JK, Williams SC. In vivo monitoring of
cellular transplants by magnetic resonance imaging and positron emission
tomography. Expert Opin Biol Ther. 2004 Feb;4(2):145-55. Review. PubMed PMID: 14998774.
1. Modo M, Williams SCR. Molecular imaging by magnetic resonance
imaging: The next generation. Rivista di Neuroradiologia. 2003 16(Suppl 2), 23-27.
Book Chapters
19. Modo, M., Hitchens, T.K. (submitted). 19F MRI imaging. In Ahrens,
E.T., Flogl, U. (Eds).
18. Dukes, M.W., Modo, M., Meade, T.J. (submitted). Non-invasive
detection of stem cell therapies facilitated by metal ion-based contrast agents.
In Meade, T.J. (Ed.)
17. Bulte, J.W. & Modo, M.
(2017). Nanoparticles as a technology platform for biomedical imaging. In Bulte,
J.W. & Modo, M. (Eds.). Design and applications of nanoparticles in
biomedical imaging. Springer Verlag.
16. Modo, M., Braga, R. & Ray, H. (2015). In vivo imaging of
transplanted cells and biomaterials. In Vishawakarma, A., Shi, S., Sharpe, P.,
Wang, X. Ramalingam, M (Eds), Stem Cell Biology and Tissue Engineering in
Dental Sciences. Elsevier.
15. Modo, M. & Massensini, A. (2014). Repairing the stroke-damaged
brain: From neural stem cells to tissue engineering. In Hayat, M.A. (Ed.), Stem
Cells and Cancer Stem Cells (Vol 12). Springer Verlag.
14. Chung, C.H., Nicholls, F., & Modo, M. (2013). Image-guided
injection and non-invasive monitoring of regeneration in the stroke-damaged
brain. In Walczak, P. & Jolkkonen, J. (Eds), Cell-based therapies in stroke.
CRC Press.
13. Nicholls, F., Gorenkova, N., Bible, E., Franco,
C., Chau, D.Y., Shakesheff, K.M., West, J.L., Modo, M. (2013). Improving the
treatment of stroke through nanotechnology. In Heiss, J.D. & Kateb, B
(eds), Nanoneurosurgery and nanoneuroscience. CRC Press.
12. Modo, M. (2011). Tracking transplanted cells by
MRI – methods and protocols. In Faber, C. & Schroeder, L. (Eds.). In
vivo NMR imaging: Methods and protocols. Humana Press. PMID:
21874504.
11. Vernon, A., & Modo, M. (2011). Imaging
proteasome inhibition damage using MRI. In Modo, M. & Bulte, J.W. (Eds.). Neuroimaging – protocols and
methods. Series: Methods in Molecular Biology, 711, 487-510. Humana Press. PMID:21279619.
10. Modo, M. & Bulte, J.W. (2011). Imaging from
molecules to man – the dawn of a vitrious man. In Modo, M. & Bulte, J.W. (Eds.). Neuroimaging – protocols and
methods. Series: Methods in Molecular Biology, 711, 3-14. Humana Press. PMID:21279595.
9. Modo, M., Meade, T.J. & Mitry, R. (2009).
Liver cell labelling with MRI contrast agents (Chapter 17). In Dhawan, A.,
Hughes, R. (Eds.), Hepatocyte Transplantation. Series: Methods in Molecular
Biology, 481, 207-219. Humana Press. PMID:19096799.
8. Bulte, J.W.M. & Modo, M. (2008). The emergence
of nanoparticles as a platform technology in biomedical imaging. In Bulte,
J.W.M. & Modo, M. (Eds), Nanoparticles in biomedical imaging: Emerging
technologies and applications. Springer Verlag.
7. Modo, M., Price, J., & Williams, S.C.R.
(2008). Cell transplantation after stroke: The role of in vivo imaging. In
Schaller, B. (Ed), State-of-the-art imaging in stroke: The present state and
implication on future. Nova Medical Publishers.
6. Modo, M. & Bulte, J.W.M. (2007). What is
molecular and cellular imaging? In Modo, M. & Bulte, J.W.M. (Eds),
Molecular and Cellular MR Imaging. CRC press.
5. Modo, M. & Bulte, J.W.M. (2007). Cellular
imaging of cell transplants. In Modo, M. & Bulte, J.W.M. (Eds), Molecular
and Cellular MR Imaging. CRC press.
4. Modo, M. & Bulte, J.W.M. (2007). The outlook
of molecular and cellular MR imaging. In Modo, M. & Bulte, J.W.M. (Eds),
Molecular and Cellular MR Imaging. CRC press.
3. Modo, M. (2007). Are stem cells attracted by
pathology? – The case for serial in vivo magnetic resonance imaging. In
Fromes, Y., Tavitian, B., Ntziachristos, V., Leroy-Willig, A. (Eds), In vivo
imaging in vertebrates. John Wiley & Sons.
2. Modo, M., &
Williams, S.C.R. (2003). MRI and novel contrast agents for molecular imaging
(pp 293-322). In van Bruggen, N. & Roberts, T. (Eds). Techniques of Biomedical Imaging in
Neuroscience Research. Boca Raton, FL: CRC Press.
1. Modo, M., Zelaya, F., Lythgoe, D., Beech, J.S., & Williams, S.C.R. (2002). Contemporary neuroimaging of cerebral ischaemia (pp 37-56). In Krieglstein, J. (Ed), Pharmacology of Cerebral Ischemia 2002. Stuttgart, Germany: Medpharm Scientific Publishers.
Books
3. Modo, M. & Bulte, J.W. (2011). MR Neuroimaging
– protocols and methods. Humana Press.
2. Bulte,
J.W.M. & Modo, M. (2008). Nanoparticles
in Imaging. Springer Verlag.
1. Modo, M.
& Bulte, J.W.M. (2007). Molecular and Cellular MR imaging. CRC Press.
