Profile Detail

Joan Lacomis, MD


Interest (in 3 to 10 words):

Medical / Graduate School Pennsylvania State University
Residency The Lahey Clinic Foundation
Clinical / Post-doctoral Fellowship Body Imaging, University of Pittsburgh
& Programs
Clinical Interest Cardiothoracic Imaging
Research Interest * CoreValve Investigation: This is a multi-center study for evaluation of the clinical utility of a percutaneous aortic valve replacement. Lacomis JM is the lead radiologist at UPMC performing the pre-procedural CTA for evaluation of the access route for the device.

* MACS Cardiovascular Disease: This is a multi-center, nested cohort study for measures of subclinical cardiovascular disease and metabolic abnormalities testing the specific hypothesis that: metabolic, inflammatory, immunologic and anthropomorphic changes that are associated with HIV infection and/or HAART lead to an increased risk for subclinical CVD. Lacomis JM is one of three cardiac radiologists at UPMC performing the calcium scoring and coronary CTA on study participants.

* ACRIN 4005: Rapid Rule-Out Strategy for Low-Risk Patients with Potential ACS Study: this is a multi-center, randomized study of patients without known CAD presenting to the emergency department with chest pain and potential acute coronary syndrome. The primary objective of this study is to test the hypothesis that CTA of the coronary arteries is a safe and effective means to exclude obstructive coronary disease as a cause for acute chest pain in patients who are considered at low risk (with normal ECG and initial negative first set of troponins) and is more cost effective and time effective than the traditional "rule out" methods of serial enzymes and nuclear stress testing. Lacomis JM is the lead of three cardiac radiologists at UPMC performing and interpreting the coronary CTA on the study participants.
Selected Publications   * Ocak I, Turkbey B, Lacomis J. Constrictive Pericarditis Presenting with an Out-pouching of the Right Ventricle Free Wall Simulating an Aneurysmatic Dilatation. British Journal of Radiology March 2011; 84 (999): e58-61.

* Ocak I, Lacomis J, Deible C, Baris T, Knollmann F. Prevalence of Aortic Root Dilation in Patients with CT Angiography of the Aorta. Diagnostic and Interventional Radiology. August 2010; (Epub ahead of print)

* Wang XH, Durick J, Lu A, Herbert DL, Fuhrman CR, Lacomis JM, Britton CA, Strollo DC, Shang SS, Golla SK, Good WF. Compare Display Schemes for Lung Nodule CT Screening. Journal of Digital Imaging. April 2010; (Epub ahead of print)

* Seethala S, Jain S, Ohori NP, Monaco S, Lacomis J, Crock F, Nemec J. Focal Monomorphic Ventricular Tachycardia as the First Manifestation of Amyloid Cardiomyopathy. Indian Pacing and Electrophysiology Journal. March 2010; 10(3): 143-147.

* Simon MA, Kosaraju V, Deible C, Lacomis J, Bunner C , Mathier MA, Champion HC. Right Ventricular-Pulmonary Arterial Coupling is an Independent Predictor of Outcomes in Pulmonary Hypertension. The Journal of Heart and Lung Transplantation 2011;Accepted for oral presentation. (will forward listing after I present next month)

* Simon MA, Kosaraju V, Deible C, Lacomis J, Bunner C, Mathier MA, Champion HC. Comprehensive Assessment of Right Ventricular-Pulmonary Arterial Coupling Predicts Outcome in Pulmonary Hypertension. Circulation 122(21 Supplement):A21207, 2010

Honors and  
PubMed Publications   See a listing of publications on PubMed, a service of the National Library of medicine.